• The multi-target stool DNA (mt-sDNA) test is a non-invasive colorectal cancer (CRC) screening test that identifies biomarkers in the stool that are associated with CRC and advanced adenomas. mt-sDNA is indicated for individuals aged 45 years and older who are at average risk for CRC.1
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  • The mt-sDNA collection kit is sent directly to the patient’s home and includes step-by-step instructions for sample collection, preparation, and shipping.1
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  • The mt-sDNA screening test is indicated to screen adults of either sex, 45 years or older, who are at average risk for colorectal cancer (CRC).1 Contraindications to this screening modality include personal history of CRC, adenomas, or other related cancer; diagnosis of various associated high-risk conditions; and diagnosis of relevant familial (hereditary) cancer syndromes.1
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  • The mt-sDNA test is a CRC screening modality that can detect 11 distinct biomarkers and utilizes an algorithm to calculate a qualitative result.1,2
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Learn more about the full Indications/Contraindications for the mt-sDNA test. Please see complete prescribing information for mt-sDNA in the Cologuard Physician Brochure.


1Cologuard Physician Brochure. Exact Sciences Corporation. Madison, WI.

2Imperiale TF, Ransohoff DF, Itzkowitz SH, et al. Multitarget stool DNA testing for colorectal-cancer screening. N Engl J Med. 2014;370(14):1287-1297

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