Riskguard™ Hereditary Cancer Test is a 32-gene Next Generation Sequencing test for those who want to understand their risk of developing inherited forms of cancer, why cancer may be common in their family, and their screening options.
Understanding this can help physicians create personalized health care plans following a cancer diagnosis.
Exact Sciences has joined forces with PreventionGenetics to add Riskguard—a hereditary multi-cancer panel—to our growing portfolio of oncology tests throughout the care continuum.
INSURANCE COVERAGE
Riskguard is covered for 96% of patients with insurance. 1
Financial assistance is available for patients with and without insurance. Patients eligible for financial assistance will have no cost for testing.*
For Providers
For Patients
Inform Personalized Treatment By Uncovering Hereditary Cancer Risk
Identify germline variants that may impact clinical decision-making in breast, prostate, colorectal, ovarian, endometrial, pancreatic, gastric, and melanoma cancers.
THE RISKGUARD™ CANCER PANEL
INDIVIDUALIZED REPORT
Provides an easy-to-understand report that includes both the gene specific and familial risks associated with a patient’s result, including potential care options for treatment discussions
CLINICALLY ACTIONABLE
Analyzes and focuses on 32 clinically actionable genes informed by professional guidelines for patient management1
TRUSTED PARTNER
Offers access to genetic counseling and world-class customer service to physicians, patients, and family members for a smooth experience. For general genetic counseling information call us at 855.669.4579 or click to learn more about genetic counseling services with Genome Medical.
Utilize A comprehensive gene panel
Gain a better understanding of a patient's inherited risk by using Riskguard, a 32-gene test, to inform management and understand susceptibility of cancer.
How To Order Riskguard
- Download Order form
- Collect blood, saliva, or buccal sample and send to PreventionGenetics
- Receive results via FAX, email, or portal in approximately 18 days2
Frequently Asked Questions
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Are you ISO 15189, CAP, and CLIA accredited?
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How does a patient’s family get tested?
Contact Us
With questions about the test, order form, kits, or patient results call us at 855-669-4579
For general genetic counseling information call us at 855.669.4579 or learn more about genetic counseling services with Genome Medical
For help navigating the insurance and billing process, see our Billing and Coverage page
Know your inherited cancer risk so you can be proactive about your health
If you have already been diagnosed with cancer, knowing your inherited cancer risk gives healthcare providers the opportunity for more personalized treatment options. If you have a gene variant known to increase the risk of getting cancer, knowing your risk can guide a more specific cancer screening schedule.
Riskguard can detect gene variants associated with an increase risk for these cancers: breast, prostate, colorectal, ovarian, endometrial, pancreatic, gastric, and melanoma.
Meeting with a genetic counselor before or after your test can help you better understand the implications of your result.
How does testing help my family?
Once a person is found to have a gene variant associated with a higher risk of getting cancer, other biological family members can benefit from that information.
Family members can get the Riskguard test to see if they carry the same variant and better assess their cancer risks. A healthcare provider can guide cancer screening options based on results.
For more information about family testing, you can speak with your healthcare provider or learn more below about genetic counseling services with Genome Medical.
What do the results mean?
Riskguard test results are designed to be simple and easy-to-understand. Speaking with your healthcare provider or genetic counselor can help you better understand your results and what actions you can take.
POSITIVE
A pathogenic gene variant is found. This result does not mean you'll develop cancer. It means your risk for inherited cancer is higher than average. Specific cancer risks depend on gene.
NEGATIVE
A pathogenic gene variant is not found. While your risk for an inherited cancer condition is reduced, your cancer risks should be considered in the context of your personal and family history.
VARIANT OF UNCERTAIN SIGNIFICANCE
At least one genetic variant was found, but it is unclear if this change causes an increased risk for cancer or if it’s harmless.
Make a plan with your doctor
If you learn that you’re at an increased risk for cancer, speak with your doctor to create a plan. This may include earlier screening, medications that can help prevent cancer, and other preventive options.2
How does the testing process work?
Frequently Asked Questions
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Who is the Riskguard test appropriate for? Who should not use the test?
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Where can I find resources about genetic counseling?
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What if my insurance requires genetic counseling?
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How does my family get tested?
Contact Us
With questions about your test result and to speak with a genetic counselor Call us at 855-669-4579
For general genetic counseling information call us at 855.669.4579 or learn more about genetic counseling services with Genome Medical
For help navigating the insurance and billing process, obtaining prior authorizations, flexible payment options, and more
References
1. Full coverage is defined as 297M lives. Data from AIS Director of Health Plans.
2. Referenced with permission from the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) for Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic. V2.2022 and Genetic/Familial High-Risk Assessment: Colorectal Cancer. V2.2022. © National Comprehensive Cancer Network, Inc. 2022. All rights reserved. Accessed August 1, 2022. To view the most recent and complete version of the guidelines, go online to NCCN.org. NCCN makes no warranties of any kind whatsoever regarding their content, use or application and disclaims any responsibility for their application or use in any way.
3. Data on File.
*Fee-for service Medicaid patients may still owe a copay depending on their state plan.