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The Riskguard™ test is an assessment tool that can help uncover hereditary cancer risk. With just a simple blood or saliva sample, it checks for hereditary genetic changes that can cause an increased risk for certain cancers.
If you have a family history of cancer, the Riskguard test can help you know if you have inherited changes in your genes that are linked to cancer, and may inform risk-reducing strategies.
If you have been diagnosed with cancer, the Riskguard test can help you know about hereditary genetic changes in your genes that can assist you and your provider in making a treatment path customized to you.
Have peace of mind knowing you and your provider can form better treatment and prevention journeys guided by genetics.1-6
Take comfort in knowing we constantly monitor genetic research and we will proactively reach out with new clinically relevant results.
Receive easy-to-understand results with potential next steps for a personalized care plan.
Sometimes receiving results can be complicated. That’s why we’ve made our results easy to understand, and our dedicated support team will be here every step of the way to walk you through the process.
A negative result means you’ll have powerful information.
Knowing your result is negative may do more than put you at ease, it could also mean less frequent screenings and avoiding unnecessary treatment.7-9 You and your provider can use this information, along with your family history and other factors, to decide next steps.
A positive result does not mean you’ll develop cancer.
It means you may be at a higher risk than average, and we’re here to support you and your provider as you create a personalized prevention or treatment plan. We’ll also let you know about future changes to your results or new research that could optimize your care path.
We’ll keep you in the know.
We’ll reach out with updates that impact you after testing. Once you get your Riskguard test results, we’ll continue to monitor genetic research for critical changes. Basically, when experts discover new science that affects your genes, your cancer risk, or your treatment, we’ll let you know.*
Proactive updates and outreach
Notifications if your cancer risk changes
Data about your genes that includes an action plan
New guidelines and screening recommendations
Cutting-edge treatment options
Our premium customer service is just a phone call away, and we can answer questions big and small before, during, and after testing.
Call our customer care team at 1-866-662-6897 with general questions about the Riskguard test, billing, insurance coverage, and flexible payment plans.
Ask customer care to connect you with an independent genetic counselor for an in-depth telehealth consult.† They can help review your family history, assess your cancer risk, understand your Riskguard test results, and assist with next steps.
See if the Riskguard test is a fit
Talk with your provider to determine if it’s the right fit for you. Our customer care team can help answer questions you may have about the Riskguard test.
Take the test
The Riskguard test will need to be ordered by your provider and performed in-office. We offer blood and saliva test kits, so you and your provider can choose what’s best.
Get your results
Your provider will review your results with you and design a customized plan. For help understanding your results or exploring your care options, we can connect you to a genetic counselor.
Coverage for eligible patients including Medicare and commercial insurance
Specialized support for billing insurance and prior authorization
Flexible payment options
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How much does this test cost?
The Riskguard test is covered by many insurance plans, including Medicare and many state Medicaid programs for patients who meet medical criteria. We also offer interest-free flexible payment options. For additional information about billing please contact 1-866-662-6897.
Does a doctor have to order my test? Or can I order a test for myself?
You cannot order the test yourself. The Riskguard test must be ordered by your healthcare provider and will be performed during your office visit. We offer both blood and saliva tests so you and your provider can decide which option is best for you.
How long does it take to get my results back?
Your healthcare provider will receive your results in approximately 14 to 21 days‡. Then they will review your results and design a customized plan with you. For additional help understanding your results or exploring your care options, contact Customer Care for assistance at 1-866-662-6897.
With questions about ordering the Riskguard test, insurance billing and payment options, checking results, or getting connected with a genetic counselor, call us at 1-866-662-6897 or email us at riskguard@exactsciences.com.
*The terms of this product offering are subject to change and not offered permanently or in perpetuity. Any modifications are to be considered effective once published on this website
†An independent genetic counselor may charge a fee for their services.
‡Data on file
References
1Geyer CE Jr, Garber JE, Gelber RD, et al; OlympiA Clinical Trial Steering Committee and Investigators. Overall survival in the OlympiA phase III trial of adjuvant olaparib in patients with germline pathogenic variants in BRCA1/2 and high-risk, early breast cancer. Ann Oncol. 2022;33(12):1250-1268.
2Hussain M, Mateo J, Fizazi K, et al; PROfound Trial Investigators. Survival with olaparib in metastatic castration-resistant prostate cancer. N Engl J Med. 2020;383(24):2345-2357.
3Golan T, Hammel P, Reni M, et al. Maintenance olaparib for germline BRCA-mutated metastatic pancreatic cancer. N Engl J Med. 2019;381:317-327.
4Ledermann J, Harter P, Gourley C, et al : Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: A preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial. Lancet Oncol 2014;15:852-861.
5Domchek SM, Friebel TM, Singer CF, et al. Association of risk-reducing surgery in BRCA1 or BRCA2 mutation carriers with cancer risk and mortality. JAMA. 2010;304(9):967-975.
6Ladabaum U, Wang G, Terdiman J, et al. Strategies to identify the Lynch syndrome among patients with colorectal cancer: a cost-effectiveness analysis. Ann Intern Med. 2011;155(2):69-79.
7Robson et al N Engl J Med. 2017; 377:523-533
8Tischler et al Ann Intern Med. 2019 Dec 17;171(12):925-930
9Kurian et al J Clin Oncol. 2011 Dec 1;29(34):4505-9
The Exact Sciences Riskguard test was developed, and its performance characteristics validated by an Exact Sciences laboratory following College of American Pathologists (CAP) and Clinical Laboratory Improvement Amendments (CLIA) regulations. The test is performed in Marshfield, WI at PreventionGenetics LLC, a wholly owned subsidiary of Exact Sciences. PreventionGenetics is accredited by CAP, certified under CLIA regulations, and qualified to perform high-complexity clinical laboratory testing. It has not been cleared or approved by the US Food and Drug Administration or other notified regulatory authority.