Gene information
The Riskguard® test gene information
Browse the resources below to learn more about each gene the test evaluates. Please discuss your Riskguard test results with a healthcare provider.
The Riskguard test checks genes across 11 cancer types
Approximately 1 in 8 cancers are due to a hereditary syndrome.1 The Riskguard test evaluates 59 different genes, so patients can learn more about their genetic risk for some of the most common and aggressive cancer types.
Learn more about the genes we evaluate
The Riskguard test can give you powerful information about your hereditary risk for cancer. Patients with a family history of cancer can gain insights into their options to reduce risk, as well as screening recommendations. Patients already diagnosed with cancer can learn how their results could inform treatment or screening.
A negative result means you’ll have powerful information
Negative results could mean less frequent screenings and avoiding unnecessary treatment.2-4 Patients and providers can use this information, along with family history and other factors, to decide next steps.
A positive result does not mean you’ll develop cancer
A positive result does not mean a patient will develop cancer; it means they may be at a higher risk than average. We’re here to support patients and providers as you create a personalized prevention or treatment plan.
An uncertain result means there’s not enough data
An uncertain result means there isn't enough data available to determine whether a gene change increases cancer risk or not. As new research is conducted, more information could be made available.
Individual gene information
Download information on each gene the Riskguard test checks. Learn what a positive result could mean, see recommendations for monitoring and surveillance, and learn how the results could impact family members.
A - C
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D - F
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G - L
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M - O
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P - R
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S - T
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U - Z
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We're here for you
With questions about ordering the Riskguard test, insurance billing and payment options, checking results, or getting connected with a genetic counselor, call us at +1 866-662-6897 or email us at riskguard@exactsciences.com .
References and footnotes
The Exact Sciences Riskguard test was developed, and its performance characteristics validated by an Exact Sciences laboratory following College of American Pathologists (CAP) and Clinical Laboratory Improvement Amendments (CLIA) regulations. The test is performed in Marshfield, WI at PreventionGenetics LLC, a wholly owned subsidiary of Exact Sciences. PreventionGenetics is accredited by CAP, certified under CLIA regulations, and qualified to perform high-complexity clinical laboratory testing. It has not been cleared or approved by the US Food and Drug Administration or other notified regulatory authority. Genomic Health, Inc., an Exact Sciences company, is the billing entity for the Riskguard test.